
Nano-bubble Contrast Agents
High-efficiency, stable contrast agent providing reliable support for blood-brain barrier opening

Product Overview
The NanoBubble Contrast Agent is a high-efficiency contrast agent designed for ultrasound-mediated blood-brain barrier (BBB) opening research and also suitable for high-resolution ultrasound imaging. Produced using advanced fabrication technology, it features uniform particle size and excellent stability. Under ultrasound exposure, it generates stable cavitation effects, significantly improving the accuracy and reproducibility of BBB opening.
Nanobubbles exhibit excellent biocompatibility and safety, making them widely used in cutting-edge research areas such as Alzheimer's disease, brain tumors, and gene therapy.
Inquire about this productCore Technical Specifications

Particle size range
170-200 nm, uniform particle size, capable of passing through capillaries
Stability
Once activated, refrigeration maintains stability for approximately 8 hours, meeting experimental workflow requirements.
biocompatibility
Excellent biocompatibility, high safety profile, and minimal side effects
Use Cases
Blood-brain barrier opening, enhanced ultrasound imaging, and drug delivery

Mechanism of Action
Ultrasound Response
Generate stable vibrations under focused ultrasound to produce mechanical effects.
Barrier Open
Microbubble vibrations temporarily loosen tight junctions between cerebral vascular endothelial cells, enabling reversible opening of the blood-brain barrier.
Auto-recovery
Blood-brain barrier automatically restores within hours, ensuring high safety and no disruption to normal physiological functions.
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